Authorized patent£º
| Name |
CN Patent Number |
| Recombined vaccine with yellow fever virus as vector |
CN200410058923.9 |
| Anti-human papillomavirus vaccine |
CN200410003395.7 |
| Vaccine with RNA recombined replicon of dengue fever virus |
CN200410003396.1 |
| Hepatitis B virus and japanese encephalitis virus recombined vaccine |
CN200410031768.1 |
| Device for powder form medicine delivery |
CN200520043682.0 |
| Method of rapid screening for sensitive anti-pathogenic micro-organism drugs |
CN200310120837.1 |
| Device of rapid screening for sensitive anti-pathogenic micro-organism drugs |
CN200320131549.1 |
Grants£º
| Title |
Supported by |
Granted |
| Research of an extract from Eucalyptus globules as an anti-cancer drug |
Committee of Science and Technology of Shanghai |
2003 |
| Study of the mechanisms of anti-prostate cancer of vitamin E derivatives |
NSF of China |
2004 |
| Study of salvianolic acid B as a new anti-cancer drug |
Committee of Science and Technology of Zhuhai, Guangdong Provine |
2004 |
| Application of gene knockout animal model in new drug safety evaluation |
Committee of Finance of Shanghai |
2005 |
| Study on XIAO CHAI HU Decoction hepatic toxicity and new recipes for toxicity alleviation |
Committee of Science and Technology of Shanghai |
2005 |
| Study of an anti-cervical cancer vaccine |
Zhangjiang Hi-tech Park, Shanghai |
2006 |
| Study of an anti-human papillomavirus vaccine |
Pudong New Area, Shanghai |
2006 |
| Vaccine with RNA recombined replicon of dengue fever virus |
Pudong New Area, Shanghai |
2006 |
| Study on the usage of Seeds of Cannabis sativa L |
Committee of Science and Technology of Shanghai |
2007 |
| Study of a therapeutic anti-cervical cancer vaccine |
Committee of Science and Technology of Beijing |
2006 |
| Preclinical study of Hepatitis B virus and Japanese encephalitis virus recombined vaccine |
Committee of Science and Technology of Beijing |
2004 |
| Pilot study of the application of a rapid screening device for sea food pathogeny |
Dept of Science and Technology and Dept of Agriculture of China |
2004 |
| Study on the drug resistancy of seafood bacteria and establishment of its monitoring system |
Dept of Science and Technology of China |
2004 |
| Study on the drug resistant bacteria in Beijing |
Committee of Science and Technology of Beijing |
2005 |
Publications£º
| Watson E, Xie T, Gu X. Apoptotic effect of salvianolic acid B in oral cancer cells. The 32nd Annual Meeting and Exhibition of the AADR, San Antonio, TX, March 12-15, 2003, http://iadr.confex.com/iadr/2003SanAnton/techprogram/abstract_28225.htm |
| Gu X, Pang X, Zhou Y, et al. Nicotine inhibits vitamin E succinate induced apoptosis of human head neck squamous cell carcinoma. American Association for Cancer Research (AACR) 2003 Annual Meeting, July 11-14, 2003, Washington, DC. AACR Abstract Number: 3894, http://www.annieappleseedproject.org/nicinvitesuc.html |
| Schwartz JL, Muscat JE, Baker V, Larios E, Stephenson GD, Guo W, Xie T, Gu X, Chung FL. Oral cytology assessment by flow cytometry of DNA adducts, aneuploidy, proliferation and apoptosis shows differences between smokers and non-smokers. Oral Oncol. 2003;39(8):842-54 |
| Zhu H, Xie T, Gu X, Yang Y, Ge M, Song X, Xue J, Ji H. Antitumor Effect of Salvianolic acid B. Chin J Prac Med 2004;4(24):2224-6 |
| Gu X, Xie T, Chen Y, Ji H.£¬Guo Y, Pang X. Chemoprevention: New anticancer strategy of the United States. Science, China 2004;56(3):8-11 |
| Zhu H, Yang Y, Xie T, Gu X, Ge M, Song X, Xue J Ji H. Antitumor Effects of Artemisinin, Dihydroartemisinin, Artemisunate and Artemether. Chin J Prac Med 2004;4(11):967-9 |
| Yang Y, Wu Y, Zhu H, Lou Z, Xie T, Liu Y, Gu X, Ji H, Ge M, Xue J, Song X. Antitumor Effects of Triterpenoids in the Fruit of Eucalyptus globules. Chin J Prac Med 2004;4(24):2209-11 |
| Tianpei Xie, Hongguang Ji, Hongli Zhu, Xinbin Gu, Xiaowu Pang, Yanfei Zhou, Rajagopalan Sridhar, Joseph Califano. Evaluation of the antitumor activity of Salvianolic Acid B in various cancer cell lines. 10th International Symposium of the Society of Chinese Bioscientists in America (SCBA), Beijing, July 18-23, 2004, Abstract P2-03-53 |
| Xinbin Gu, Xiaodong Song, Rajagopalan Sridhar, Tianpei Xie, Joseph Califano. Nicotine Effects in Cancer Prevention and Therapy. 10th International Symposium of the Society of Chinese Bioscientists in America (SCBA), Beijing, July 18-23, 2004, Abstract P2-03-39 |
| Xiaowu Pang, Xinbin Gu,Tianpei Xie. Pseudo virus-like particles of dengue virus replicon at therapeutic vaccine vector. 10th International Symposium of the Society of Chinese Bioscientists in America (SCBA), Beijing, July 18-23, 2004, Abstract P2-12-06 |
| Xie T, Gu X, Zhu H, Ji H. Hollow fiber assay: an efficient in vivo anticancer drug screening model. Chin J Pharmacol 2005;40(6):469-470 |
| W Sui, Q Yan, H Chen, L Bi. Effects of grapefruit abstracts on the activity of mice liver microsomes. J Digestive Surgery 2005;4(5):364-7 |
| Guo Y, Wang X, Pang X, Gu X. ¡°Technology of Development Flaviviruses Vector.¡± Chinese Journal of Virology, 2005;21:497-500. |
| Xiaodong Song, Wei Tian, Shaofeng Jiang, Yuyong Wu, Guanying Wei, Junhou Yang, Yinhan Guo. Prostate Cancer- Suppressing Function of Salvianolic acid B. Chinese Journal of Traditional and Western Medicine. 2005,6(11) |
| Yinhan Guo, Xiaopeng Wang, Xiaowu Pang, Xinbin Gu. Drug Delivery Vector Derived from Flavivirus, Chinese Journal of Virology. 2005, 21(6), 497-500 |
| Dawei Li, Xiaoqiang Yang. Fast Method of Screening Antimicrobial Susceptibility for Infective Diseases in Fishery. Fishery Modernization. 2005,1,27-28 |
| Li Zhou, Xiang Gao. A new diagnosis and treatment kit for Infective Diseases. China Fisheries. 2005, 7,86-87 |
| Pang X, Fu W, Guo Y, Zhang L, Xie T, Gu X. ¡°Construction of recombinant yellow fever virus 17D containing 2A fragment as a vaccine vector. Chinese Journal of Biotechnology 2006;22:492-8. |
| Ge M, Xie T, Ji H. Food and drug interactions. Chin J Prac Med 2006;6(5):428-31 |
| Gu X, Schwartz JL, Pang X, Zhou Y, Sridhar R. ¡°Cytotoxicity of liposomal ?-tocopheryl succinate towards hamster cheek pouch carcinoma (HCPC-1) cells in culture¡± Cancer Letters 2006;239:281-91. |
| Jun Wei, Yinhan Guo. Drug resistance Analysis of Pathogen In Chicken Farms, Zhengding, Shijiazhuang. Guide To Chinese Poultry. 2006,23(5),43 |
| Xiaowu Pang, Wenchuan Fu, Yinhan Guo, Lishu Zhang, Tianpei Xie, Xinbin Gu. Construction of Recombinant Yellow Fever Virus 17D Containing 2A Fragment as a Vaccine Vector. Chinese Journal of Biotechonlogy. 2006, 22(3), 492-498 |
| GE Meng, CHAI Yi-feng, JI Hong-guang, CHENG Jing-jing, LI Yu-qi, WU Feng, XIE Tian-pei. In Vitro Detection of Human Liver Cells Toxicity Induced by Various Recipes of XIAO CHAI HU Decoction. Academic J SMMU 2007;28(11):1266-8 |
| Song X, Zhao D, Yang J, Yang Y, and Gu X. ¡°Vitamin E succinate induced apoptosis in oral squamous cell carcinoma Tca8113 cells¡± BMU Journal 2007;30:85-6. |
| Xiaodong Song, Ming Yang, Junhou Yang, Xiuhua Tan, Yinhan Guo. The effect of salvianolic acid B on a nontumorigenic human prostatic epithelial cell line. Journal of Binzhou Medical University. 2007, 30(1) :11-12 |
| Gu X, Song X, Dong Y, Pang X, Walters E, Cai H, Zhang R, Xie T, Guo Y, Califano J. ¡°Vitamin E Succinate Induces Ceramide-mediated Apoptosis in Human Head and Neck Squamous Cell Carcinoma in vitro and in vivo¡±. Clinical Cancer Research 2008;15:1840-8. |
| Dong Y, Guo Y, Gu X. ¡°Anticancer Mechanisms of Vitamin E Succinate¡± Chinese Journal of Cancer 2008; [Epub ahead of print] |
| Hao Y, Xie T, Korotcov A, Zhou Y, Pang X, Shan L, Ji H, Sridhar R, Wang P, Califano J, Gu X. ¡°Salvianolic Acid B Inhibits Growth of Head and Neck Squamous Cell Carcinoma in vitro and in vivo via Cyclooxygenase-2 and Apoptotic Pathways¡± Int J Cancer 2008 Nov 19. [Epub ahead of print] |
| Hao Y, Zhou Y, Ji H, Fang Y, Pang X, Southerland M, Califano J, Gu X. Salvianolic acid B specifically inhibits cyclooxygenase-2 in human cancer cell lines. 99th AACR Annual meeting£¬ 2008 |
| Sha W, Zhou Y, Ji H, Shan L, Pang X, Califano J, Gu X. Salvianolic acid B, a natural compound, showing anti-cancer activity by inhibiting breast cancer cell proliferation and inducing cell apoptosis. 100th AACR Annual meeting, 2009 |
| Zhao Y, Hao Y, Dong Y, Guo Y, Califano J, Gu X. Combinatorial Effect of Salvianolic Acid B and Celecoxib on Inhibition of Head and Neck Squamous Cell Carcinoma. 100th AACR Annual meeting, 2009 |
| Hao Y, Pang X, Dong Y, Zhao Y, Califano J, Gu X. Variation of miRNA expression in cultured human prostate cancer cell lines and their xenograft tumors. 100th AACR Annual meeting, 2009 |
| Zhao Y, Hao Y, Ji H, Guo Y, Zhou Y, Califano J, Gu X. Combinatorial Effect of Salvianolic Acid B and Celecoxib on Inhibition of Head and Neck Squamous Cell Carcinoma. 2009 (in press) |
| Hao Y, Xie T, Dong Y, Zhou Y, Sridhar R, Ji H, Califano J, Gu X. Salvianolic Acid B Selectively Inhibits Growth of Benign Prostatic Hyperplasia and Prostate Cancer in Vitro and in Vivo through Mediating Cell Proliferation and Death. 2009 (in press) |
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